Marine Chemistry / Alfa Chemistry
α-Conotoxin AuIA
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α-Conotoxin AuIA

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Description

α-Conotoxin AuIA is a peptidyl toxin composed of 16 amino acids and is classified under the neuronal α 4/7 subfamily of α-conotoxins that can be isolated from Conus aulicus. The toxin is selective and potently inhibits the α3β4 nicotinic acetylcholine receptor (nAChR) channel. This specificity makes it a valuable tool for probing the physiology of nicotinic acetylcholine receptors and exploring potential therapeutic applications.

Specification

Itemα-Conotoxin AuIA
CatalogMC216299206
CAS216299-20-6
Molecular FormulaC72H96N18O24S4
Molecular Weight1725.90
Purity>98%
SequenceGly-Cys-Cys-Ser-Tyr-Pro-Pro-Cys-Phe-Ala-Thr-Asn-Ser-Asp-Tyr-Cys-NH2 (Disulfide bridge: Cys2-Cys8, Cys3-Cys16)
Sequence ShorteningGCCSYPPCFATNSDYC-NH2 (Disulfide bridge: Cys2-Cys8, Cys3-Cys16)
Length (AA)16
Peptide Content100%
FormLyophilized powder
SourceSynthetic peptide
StorageProduct as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20 °C.
SolubilityAny aqueous buffer
Storage of SolutionsUp to two weeks at 4 °C or three months at -20 °C.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.