Description

α-Conotoxin AuIA is a peptidyl toxin composed of 16 amino acids and is classified under the neuronal α 4/7 subfamily of α-conotoxins that can be isolated from Conus aulicus. The toxin is selective and potently inhibits the α3β4 nicotinic acetylcholine receptor (nAChR) channel. This specificity makes it a valuable tool for probing the physiology of nicotinic acetylcholine receptors and exploring potential therapeutic applications.
Specification
Item | α-Conotoxin AuIA |
---|
Catalog | MC216299206 |
CAS | 216299-20-6 |
Molecular Formula | C72H96N18O24S4 |
Molecular Weight | 1725.90 |
Purity | >98% |
Sequence | Gly-Cys-Cys-Ser-Tyr-Pro-Pro-Cys-Phe-Ala-Thr-Asn-Ser-Asp-Tyr-Cys-NH2 (Disulfide bridge: Cys2-Cys8, Cys3-Cys16) |
Sequence Shortening | GCCSYPPCFATNSDYC-NH2 (Disulfide bridge: Cys2-Cys8, Cys3-Cys16) |
Length (AA) | 16 |
Peptide Content | 100% |
Form | Lyophilized powder |
Source | Synthetic peptide |
Storage | Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20 °C. |
Solubility | Any aqueous buffer |
Storage of Solutions | Up to two weeks at 4 °C or three months at -20 °C. |
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.