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α-Tocopherol
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α-Tocopherol

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The structure of alpha-tocopherol.
  • Catalog: MC59029
  • Product Name: α-Tocopherol
  • CAS: 59-02-9
  • Molecular Formula: C29H50O2
  • Molecular Weight: 430.71

Introduction

α-Tocopherol, one of the eight isoforms of vitamin E, stands out as the most potent fat-soluble antioxidant found in nature. For many years, it was primarily regarded as a scavenger of lipid peroxyl radicals, particularly those associated with oxidized low-density lipoprotein (oxLDL). This role positioned α-tocopherol as a key player in antioxidant defense, significantly contributing to the prevention of atherosclerosis. However, recent research has revealed a much broader spectrum of functions for α-tocopherol. Beyond its well-known antioxidant properties, it also exhibits pro-oxidant capabilities, plays a critical role in cell signaling, and influences gene regulation. As one of the most biologically active forms of vitamin E, α-tocopherol has the potential to prevent and treat a variety of human diseases.

Specification

Itemα-Tocopherol
CatalogMC59029
CAS59-02-9
FormLiquid
ColorColorless to light yellow
Purity98%
Melting Point200-220 °C
Density0.95 g/mL at 25 °C (lit.)
Potency~1000 IU/g
MDLMFCD00072045
InChI1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1
InChI KeyGVJHHUAWPYXKBD-IEOSBIPESA-N
Storage4 °C, protect from light, stored under nitrogen

Pharmaceutical Application

α-Tocopherol has the potential to prevent and treat cardiovascular disease, cancer, and Alzheimer's disease.

  • α-Tocopherol scavenges free radicals, reducing oxidative stress which is a key contributor to atherosclerosis and other cardiovascular issues.
  • α-Tocopherol is able to eliminate free radical damage, induce apoptosis, and influence the expression of oncogenes, making it a strong candidate for chemotherapeutic strategies.
  • Alzheimer's disease is the most common neurodegenerative disease. α-Tocopherol may protect neurons from oxidative damage, which is implicated in the pathology of Alzheimer's disease.

Choose Alfa Chemistry

Alfa Chemistry is a professional α-tocopherol supplier and has always been committed to producing high-quality α-tocopherol. We strictly control the quality management to ensure that the α-tocopherol we provide is safe. If you want to know more, please feel free to contact us.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.