Description
The macrolide compound aplasmomycin is a class of antibiotics produced by Streptococcus griseus isolated from shallow marine mud, which has shown inhibitory effects against Gram-positive bacteria in vitro and antimalarial effects in vivo. In this natural product, boron plays a structural role, inducing the folding of polyols into a compact structure. Its distinctive mechanism of action targets bacterial cell walls, disrupting their growth and proliferation, which makes it a promising candidate for treating infections that are unresponsive to conventional antibiotics.
Specification
| Item | Aplasmomycin |
|---|
| Catalog | MC61230259 |
| CAS | 61230-25-9 |
| Molecular Formula | C40H60BNaO14 |
| Molecular Weight | 798.70 |
| Melting Point | 283-285 °C |
| Form | Colorless needle-shaped crystals |
| InChI Key | GEIYDRPAWIMINR-ZDKANEFWSA-N |
| InChI | 1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h7,10,19-20,23-27,30H,8-9,11-18H2,1-6H3/b21-7+/t20-,23+,24+,25-,26+,27+,28+,29-/m1/s1 |
| SMILES | [B-]123O[C@]45O[C@H](C([C@@H](C/C=C/[C@H]6O[C@@H]([C@H](C6)OC(=O)[C@H](O1)[C@]7(O2)O[C@H](C([C@@H](C/C=C/[C@H]8O[C@@H]([C@H](C8)OC(=O)[C@@H]4O3)C)O)(C)C)CC[C@H]7C)C)O)(C)C)CC[C@H]5C.[Na+] |
| Storage | Store in cool place. |
Choose Alfa Chemistry
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.
