Azaspiracid-1

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Description

Azaspiracid-1 is a marine biotoxin produced by specific species of dinoflagellates, particularly from the genera Azadinium and Amphidoma. It is known for causing azaspiracid shellfish poisoning (AZP), a syndrome characterized by gastrointestinal symptoms such as diarrhea, vomiting, and stomach cramps. This toxin predominantly disrupts biochemical pathways related to energy metabolism and ion homeostasis. It hinders endocytosis and leads to a temporary depletion of ATP, an essential molecule for cellular energy transfer. Additionally, it increases cytosolic calcium levels, which can significantly impact various cellular processes.

Specification

Item	Azaspiracid-1
Catalog	MC214899215
CAS	214899-21-5
Molecular Formula	C₄₇H₇₁NO₁₂
Molecular Weight	842.07
Purity	>99%
Solubility	Soluble in water, and methanol.
Appearance	Colorless amorphorous solid
Canonical SMILES	CC1CC2C3C(CC4(O3)C(CC(CN4)C)C)OC(C1)(O2)CC(=C)C5C(CC(C(O5)(C(C6CC7C(O6)CC(C8(O7)CCC9(O8)C=CCC(O9)C=CCCC(=O)O)C)O)O)C)C
Isomeric SMILES	CC1CC2C3C(C[C@@]4(O3)C(CC(CN4)C)C)O[C@@](C1)(O2)CC(=C)C5C(CC([C@@](O5)(C(C6CC7C(O6)CC([C@@]8(O7)CC[C@@]9(O8)C=CCC(O9)C=CCCC(=O)O)C)O)O)C)C
InChi Code	InChI=1S/C47H71NO12/c1-26-18-36-41-38(24-45(58-41)30(5)17-27(2)25-48-45)56-44(22-26,55-36)23-29(4)40-28(3)19-32(7)47(52,59-40)42(51)37-21-35-34(53-37)20-31(6)46(57-35)16-15-43(60-46)14-10-12-33(54-43)11-8-9-13-39(49)50/h8,10-11,14,26-28,30-38,40-42,48,51-52H,4,9,12-13,15-25H2,1-3,5-7H3,(H,49,50)/t26?,27?,28?,30?,31?,32?,33?,34?,35?,36?,37?,38?,40?,41?,42?,43-,44+,45+,46+,47+/m0/s1
InChi Key	AHFHSIVCLPAESC-SLHHEBIUSA-N
Storage Temperature	Store at -20 °C

Research Applications

Azaspiracid-1 has a variety of research applications. It serves as a vital reference standard in the detection and quantification of azaspiracids in shellfish. This application is crucial for the effective monitoring and management of shellfish poisoning risks, thereby ensuring consumer safety. This compound is also used to develop assays for marine biotoxins in seafood, which aids in food safety and public health. Moreover, it plays a key role in structure-activity relationship studies, which aim to unravel the molecular mechanisms underlying its toxicological effects. These studies provide invaluable insights into the interactions between this toxin and its cellular targets, contributing to a deeper understanding of its impact on biological systems.

Choose Alfa Chemistry

Alfa Chemistry is dedicated to maintaining the highest standards of quality while continually pursuing innovative solutions. Our mission is to harness the vast potential of marine resources and offer a wide array of premium products. We take pride in our capability to supply high-quality azaspiracid-1 at a competitive price. Should you have any inquiries or specific needs, please do not hesitate to reach out to us. We look forward to assisting you!

For Research Use Only. Not for use in diagnostic or therapeutic procedures.