Azaspiracid-4

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Description

Azaspiracid-4 is a member of the azaspiracid family of marine toxins, which are produced by dinoflagellates of the genera Azadinium and Amphidoma. It can accumulate in shellfish, causing azaspiracid shellfish poisoning (AZP). This compound has been the subject of extensive research due to its potent bioactivity and potential health risks.

Specification

Item	Azaspiracid-4
Catalog	MC344422497
CAS	344422-49-7
Molecular Formula	C₄₆H₆₉NO₁₃
Molecular Weight	844.04
Purity	>98%
Solubility	Soluble in methanol.
Canonical SMILES	CC1CCC(OC1C(=C)CC23CC(CC(O2)C4C(O3)CC5(O4)C(CC(CN5)C)C)C)(C(C6CC7C(O6)CC(C8(O7)CCC9(O8)C=CCC(O9)C=CC(CC(=O)O)O)C)O)O
Isomeric SMILES	C[C@H]1CC[C@@](O[C@@H]1C(=C)C[C@]23C[C@@H](C[C@H](O2)[C@H]4[C@@H](O3)C[C@@]5(O4)[C@@H](C[C@@H](CN5)C)C)C)([C@H]([C@H]6C[C@H]7[C@@H](O6)C[C@@H]([C@@]8(O7)CC[C@@]9(O8)C=CC[C@H](O9)/C=C/[C@@H](CC(=O)O)O)C)O)O
InChi Code	InChI=1S/C46H69NO13/c1-25-17-35-40-37(23-44(58-40)29(5)16-26(2)24-47-44)56-43(21-25,55-35)22-28(4)39-27(3)11-13-45(52,59-39)41(51)36-20-34-33(53-36)18-30(6)46(57-34)15-14-42(60-46)12-7-8-32(54-42)10-9-31(48)19-38(49)50/h7,9-10,12,25-27,29-37,39-41,47-48,51-52H,4,8,11,13-24H2,1-3,5-6H3,(H,49,50)/b10-9+/t25-,26+,27+,29-,30+,31+,32+,33+,34+,35+,36-,37+,39+,40+,41+,42+,43-,44-,45-,46-/m1/s1
InChi Key	OVUUSRBSEMRJGT-JOAUMJRMSA-N
Storage Temperature	Store at -20 °C

Mechanism of Action

Azaspiracid-4 exerts its effects by interacting with ion channels and other cellular targets, although the precise molecular targets remain not entirely elucidated. Research indicates that azaspiracids can influence ion channel activity, thereby disturbing cellular homeostasis. These disruptions may lead to a range of toxic effects, including gastrointestinal symptoms and potentially long-term health consequences.

Research Applications

Azaspiracid-4 holds significant importance across various fields due to its unique properties and potent biological activity. In the field of chemistry, it serves as a model compound for exploring the reactivity and stability of marine toxins. This contributes to a better understanding of how such toxins behave and interact in marine environments. Meanwhile, in biology and medicine, azaspiracid-4 is used to gain insights into the mechanisms behind toxin-induced cellular damage, as well as to develop effective detection methods for shellfish contamination. Furthermore, its distinct structure makes it an invaluable tool for studying ion channel activity and other vital cellular processes.

Choose Alfa Chemistry

Alfa Chemistry is dedicated to maintaining the highest standards of quality while continually pursuing innovative solutions. Our mission is to harness the vast potential of marine resources and offer a wide array of premium products. We take pride in our capability to supply high-quality azaspiracid-4 at a competitive price. Should you have any inquiries or specific needs, please do not hesitate to reach out to us. We look forward to assisting you!

For Research Use Only. Not for use in diagnostic or therapeutic procedures.