Ciguatoxin-2

Inquiry

Description

Ciguatoxin-2 is a potent marine neurotoxin produced by certain species of dinoflagellates, primarily from the genera Gambierdiscus and Fukuyoa, found in tropical and subtropical waters. This toxin is a variant of ciguatoxin with a complex polyether structure. Ciguatoxin-2, like its counterparts, disrupts cellular ion channels, particularly affecting sodium channels. Binding of ciguatoxin-2 to these channels results in prolonged depolarization and increased neuronal excitability, leading to a range of neurotoxic symptoms in humans, including gastrointestinal, neurological, and cardiovascular disturbances.

Specification

Item	Ciguatoxin-2
Catalog	MC142185851
CAS	142185-85-1
Synonyms	CTX-2
Molecular Formula	C₆₀H₈₆O₁₈
Molecular Weight	1095.33
Purity	>95%
Appearance	White powder
SMILES	CC1CC2C(CC3C(O2)C(C(C4C(O3)C(C(C5(O4)CCCO5)C)C)O)C)OC6CC7C(C(CC8C(O7)CC=CCC9C(O8)C=CC2C(O9)C=CC3C(O2)CC2C(O3)C(C3C(O2)CC=CC(O3)C=CC(CO)O)O)O)(OC6C1)C
InChi Code	InChI=1S/C60H86O18/c1-29-22-42-44(25-48-54(75-42)31(3)52(64)58-55(76-48)30(2)32(4)60(78-58)20-9-21-66-60)72-46-27-51-59(5,77-47(46)23-29)50(63)26-45-36(73-51)12-7-6-11-35-37(70-45)16-17-39-38(68-35)18-19-40-43(69-39)24-49-57(74-40)53(65)56-41(71-49)13-8-10-34(67-56)15-14-33(62)28-61/h6-8,10,14-19,29-58,61-65H,9,11-13,20-28H2,1-5H3/b7-6-,15-14+/t29-,30+,31+,32+,33+,34-,35-,36+,37+,38+,39-,40-,41+,42+,43+,44-,45-,46+,47-,48+,49-,50-,51-,52+,53-,54-,55-,56+,57-,58+,59+,60+/m1/s1
InChi Key	RWSYPPRKMNWNII-VYQNUHOXSA-N
Storage Temperature	Store at -20 °C.

Applications

Chemical research. Ciguatoxin-2 serves as a valuable model compound in the field of chemistry, particularly for the study of complex polyether synthesis. Its structural intricacies provide researchers with insights into the challenges of synthesizing similar polyether compounds.
Neuropharmacology research. Ciguatoxin-2 serves as a valuable tool for studying ion channel physiology, particularly voltage-gated sodium channels. It helps in understanding the mechanism of action of neurotoxins and their effects on neuronal excitability.
Food safety monitoring. Ciguatoxin-2 contributes to the development of detection methods for ciguatoxins in seafood. This is crucial for preventing ciguatera fish poisoning, which can occur when humans consume contaminated fish.

Choose Alfa Chemistry

At Alfa Chemistry, we specialize in the production of high-quality marine toxins. Our expertise in marine chemistry ensures that our products meet the highest standards of purity and potency, making them ideal for various applications in research, pharmaceuticals, and biotechnology. We are able to offer ciguatoxin-2 at competitive prices. Should you have any specific requirements or inquiries, please do not hesitate to reach out to us. We are enthusiastic about assisting you and look forward to the opportunity to serve your needs effectively.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.