Description
Decarbamoylgonyautoxin 2 is a natural marine toxin derived from the decarbamoylation of gonyautoxin-2 that can accumulate in shellfish, posing significant health risks when consumed by humans. It is a derivative of gonyautoxins, featuring a distinct chemical structure due to the absence of a carbamoyl group, which influences its binding affinity and potency towards sodium channels in nerve cells. This alteration plays a crucial role in the toxin's mechanism of action, leading to the blocking of nerve signal transmission and potentially causing severe physiological effects, such as muscle paralysis and respiratory failure.
Specification
| Item | Decarbamoylgonyautoxin 2 |
|---|
| Catalog | MC86996874 |
| CAS | 86996-87-4 |
| Synonyms | dcGTX2; DcGonyautoxin 2 |
| Molecular Formula | C9H16N6O7S |
| Molecular Weight | 352.32 |
| Purity | >95% |
| Canonical SMILES | C1C23C(C(N=C(N2C(C1(O)O)OS(=O)(=O)O)N)CO)N=C(N3)N |
| Isomeric SMILES | C1[C@]23[C@H]([C@@H](N=C(N2[C@H](C1(O)O)OS(=O)(=O)O)N)CO)N=C(N3)N |
| InChi Code | InChI=1S/C9H16N6O7S/c10-6-13-4-3(1-16)12-7(11)15-5(22-23(19,20)21)9(17,18)2-8(4,15)14-6/h3-5,16-18H,1-2H2,(H2,11,12)(H3,10,13,14)(H,19,20,21)/t3-,4-,5-,8+/m0/s1 |
| InChi Key | GBRZXCTZYCGMIE-KALNXVOASA-N |
| Storage Temperature | Store at -20 °C. |
Applications
- Research in neurophysiology and ion channel function. As a potent sodium channel blocker, decarbamoylgonyautoxin 2 is used as a pharmacological tool to study the properties, structure, and function of voltage‐gated sodium channels.
- Toxicology research. In studies of paralytic shellfish poisoning and harmful algal blooms, decarbamoylgonyautoxin 2 serves as a reference compound for developing detection assays and understanding toxin profiles in contaminated samples.
- Medical treatments. Decarbamoylgonyautoxin 2, have been investigated for its potential therapeutic applications, particularly in treating acute and chronic anal fissures. The toxin acts by relaxing the muscle in the injection area, and providing pain relief.
Choose Alfa Chemistry
At Alfa Chemistry, we are committed to maintaining the utmost standards of quality while relentlessly pursuing innovation. Our aim is to harness the vast potential of marine resources, allowing us to deliver a diverse array of outstanding products. We are proud to offer decarbamoylgonyautoxin 2 of superb quality at competitive prices. Should you have any specific requirements or inquiries, please do not hesitate to reach out to us. We are enthusiastic about the opportunity to assist you.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
