Description
Decarbamoylgonyautoxin 3 is a derivative of gonyautoxins that has undergone specific chemical modifications, most notably the removal of a carbamoyl group, which alters both its toxicological profile and its interaction with biological systems. The molecule's complex architecture includes multiple functional groups, such as amino and hydroxyl groups, which contribute significantly to its chemical reactivity and biological activity. Moreover, the presence of a hydrogen sulfate moiety indicates good aqueous solubility—an essential feature for effective biological interaction. These combined characteristics render decarbamoylgonyautoxin 3 a versatile compound with potential applications in various chemical and biochemical processes.
Specification
Item | Decarbamoylgonyautoxin 3 |
---|
Catalog | MC87038537 |
CAS | 87038-53-7 |
Synonyms | dcGTX3; DcGonyautoxin 3 |
Molecular Formula | C9H16N6O7S |
Molecular Weight | 352.32 |
Purity | >95% |
Canonical SMILES | C1C(C(C23N1C(=NC(C2N=C(N3)N)CO)N)(O)O)OS(=O)(=O)O |
Isomeric SMILES | C1[C@@H](C([C@@]23N1C(=N[C@H]([C@@H]2N=C(N3)N)CO)N)(O)O)OS(=O)(=O)O |
InChi Code | InChI=1S/C9H16N6O7S/c10-6-13-5-3(2-16)12-7(11)15-1-4(22-23(19,20)21)9(17,18)8(5,15)14-6/h3-5,16-18H,1-2H2,(H2,11,12)(H3,10,13,14)(H,19,20,21)/t3-,4-,5-,8-/m0/s1 |
InChi Key | AJLCXXKDNUGKKH-RGDLXGNYSA-N |
Storage Temperature | Store at -20 °C. |
Applications
- Studying sodium channels. Like several paralytic shellfish toxins, decarbamoylgonyautoxin 3 interacts with voltage‐gated sodium channels on nerve and muscle cells. Researchers use it to probe the structure and function of these channels, gaining insights into how they open, close, and select ions. This research is fundamental to understanding cellular excitability and communication.
- Drug discovery. Detailed knowledge of ion channel structure and function obtained through studies using decarbamoylgonyautoxin 3 can inform drug design. For example, understanding how a toxin blocks a sodium channel can lead to the development of new drugs aimed at modulating channel activity in conditions such as chronic pain, epilepsy, or other neurological disorders.
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.