Description
Didemnin B is a cyclic depsipeptide extracted from the Caribbean tunicate Trididemnun solidum and provides a unique lactoylproline unit in the side chain of the molecule. As a member of the didemnin class, it has drawn considerable interest in the pharmaceutical sector due to its potent bioactive properties. Didemnin B inhibits the synthesis of RNA, DNA, and proteins and exhibits a broad spectrum of biological activities, including antiviral, antitumor, and immunosuppressive effects, making it a promising candidate for therapeutic applications.
Specification
| Item | Didemnin B |
|---|
| Catalog | MC77327050 |
| CAS | 77327-05-0 |
| Molecular Formula | C57H89N7O15 |
| Molecular Weight | 1112.35 |
| Form | Solid |
| Purity | >99% |
| Color | White to off-white |
| InChI Key | KYHUYMLIVQFXRI-SJPGYWQQSA-N |
| Storage | Store in dry, dark conditions at 0-4 °C for short term (days to weeks) and at -20 °C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Storage of Solutions | Store at 0-4 °C for short term (days to weeks) and at -20 °C for long term. |
Biological Activities
- Antitumor activity. Didemnin B has shown significant antitumor properties and inhibits the growth of various cancer cell lines. It exerts cytotoxic effects by disrupting protein synthesis and inducing apoptosis in cancer cells.
- Immunomodulatory effects. Didemnin B has been reported to enhance immune responses. It modulates the activity of various immune cells, including T lymphocytes and natural killer (NK) cells, potentially improving the body's ability to fight tumors.
- Antiviral activity. Some studies have indicated that didemnin B possesses antiviral properties, specifically against certain types of viruses, by inhibiting their replication.
Choose Alfa Chemistry
With a strong commitment to quality and a relentless pursuit of innovation, Alfa Chemistry strives to unleash the unlimited potential of marine resources and provide a diverse range of quality products. We have the ability to provide you with high-quality didemnin B at a competitive price. If you have any requirements, please contact us immediately.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
