Gonyautoxin II

Inquiry

Description

Gonyaxin II is a naturally occurring neurotoxin produced by certain marine dinoflagellates such as Alexandrium, Gonyaulax, and Protogonyaulax. This toxin is structurally related to saxitoxins and is able to block sodium channels in nerve cells. Gonyautoxin II's molecular structure and mode of action have made it a subject of extensive research in neurochemistry and toxicology, as it provides valuable insight into nerve transmission processes and the potential development of novel pharmacological agents.

Specification

Item	Gonyautoxin II
Catalog	MC60508896
CAS	60508-89-6
Synonyms	Gonyautoxin 2; GTX II; GTX2
Molecular Formula	C₁₀H₁₇N₇O₈S
Molecular Weight	395.35
Purity	>95%
Appearance	Powder
SMILES	C1C(C(C23N1C(=NC(C2N=C(N3)N)COC(=O)N)N)(O)O)OS(=O)(=O)O
InChi Code	InChI=1S/C10H17N7O8S/c11-6-15-5-3(2-24-8(13)18)14-7(12)17-1-4(25-26(21,22)23)10(19,20)9(5,17)16-6/h3-5,19-20H,1-2H2,(H2,12,14)(H2,13,18)(H3,11,15,16)(H,21,22,23)/t3-,4+,5-,9-/m0/s1
InChi Key	ARSXTTJGWGCRRR-XXKOCQOQSA-N
Storage Temperature	Store at -20 °C

Research Applications

Neuroscience and ion channel research. Gonyautoxin II's specific interaction with voltage-gated sodium channels makes it an excellent probe for studying the structure, function, and pharmacology of these channels. Researchers use gonyautoxin II to unravel the mechanisms of ion channel gating, ion selectivity, and conformational changes during channel operation.
Pharmacological tool. By blocking sodium channels in a controlled research setting, gonyautoxin II can help scientists understand how different parts of the channel contribute to nerve signal propagation.

Toxin-mechanism studies. Studying how gonyautoxin II interact with sodium channels also aids in understanding the mechanisms of paralytic shellfish poisoning. This research is valuable not only for public health (by improving detection and management of toxin exposure) but also for broader toxicological studies involving environmental toxins.
Drug development. Gonyautoxin II and its derivatives have been explored for drug development. This compound is being investigated for potential use in pain management, particularly for conditions such as acute back pain.

Choose Alfa Chemistry

Alfa Chemistry is dedicated to maintaining the highest standards of quality while continuously pursuing innovation. Our commitment is to harness the vast potential of marine resources, allowing us to offer a diverse array of exceptional products. We are proud to provide high-quality gonyautoxin II at competitive prices. Should you have any specific requirements or inquiries, please do not hesitate to reach out to us. We look forward to assisting you.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.