Description
Gonyautoxin IV is a potent neurotoxin belonging to the group of paralytic shellfish poisons (PSPs). It is naturally produced by certain marine dinoflagellates and cyanobacteria and can accumulate in filter-feeding shellfish, posing significant risks to human and marine life when these organisms are consumed. The toxin works by blocking voltage-gated sodium channels in nerve cells, which disrupts normal nerve signal transmission and can lead to symptoms ranging from numbness and dizziness to severe paralysis. Due to its toxicity and potential impact on public health, gonyautoxin IV is a focus of extensive scientific research, particularly regarding its mechanism of action and potential applications in various fields of research.
Specification
| Item | Gonyautoxin IV |
|---|
| Catalog | MC64296260 |
| CAS | 64296-26-0 |
| Synonyms | Gonyautoxin 4; GTX IV; GTX4 |
| Molecular Formula | C10H17N7O9S |
| Molecular Weight | 411.35 |
| Purity | >95% |
| Appearance | White to light yellow crystal powder |
| SMILES | C1C(C(C23N1C(=N)N(C(C2N=C(N3)N)COC(=O)N)O)(O)O)OS(=O)(=O)O |
| InChi Code | InChI=1S/C10H17N7O9S/c11-6-14-5-3(2-25-8(13)18)17(21)7(12)16-1-4(26-27(22,23)24)10(19,20)9(5,16)15-6/h3-5,12,19-21H,1-2H2,(H2,13,18)(H3,11,14,15)(H,22,23,24)/t3-,4-,5-,9-/m0/s1 |
| InChi Key | CETRDCWBMBILAL-LJRZAWCWSA-N |
| Storage Temperature | Store at -20 °C. |
Research Applications
Gonyautoxin IV is extensively utilized in scientific research, particularly within the realm of neuroscience. It serves as a valuable tool for investigating the mechanisms underlying sodium channel function and exploring the effects of channel blockers in neurological conditions like epilepsy and chronic pain. Additionally, gonyautoxin IV plays a crucial role in the development of drugs that block sodium channels, aimed at treating a variety of diseases. Beyond its role in neuroscience, gonyautoxin IV is also employed as a biomarker for detecting PSPs in environmental samples.
Choose Alfa Chemistry
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.
