Microcystin-RR

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Description

Microcystin-RR is a cyclic heptapeptide primarily produced by species of cyanobacteria, particularly those from the genus Microcystis. It stands as one of the most prevalent variants of microcystins, notable for its stability and resistance to degradation. This toxin inhibits protein phosphatases, thereby disrupting cell signaling pathways, which may cause liver damage and lead to a range of adverse health effects. In addition, research has shown that microcystin-RR can disrupt endocrine functions and interfere with crucial biological processes, such as cholesterol synthesis and lipid oxidation in vivo. The compound is also implicated in inducing mitochondrial dysfunction and generating oxidative stress, which can lead to alterations in gonadal structure during development.

Specification

Item	Microcystin-RR
Catalog	MC111755374
CAS	111755-37-4
Synonym	Cyanoginosin-RR; MC-RR
Molecular Formula	C₄₉H₇₅N₁₃O₁₂
Molecular Weight	1038.20
Purity	>95%
Solubility	Soluble in ethanol/water mixture 1:1 (0.5 mg/mL).
Appearance	Clear film
MDL Number	MFCD00871765
SMILES	CC(/C=C/[C@H](NC([C@H](CCCNC(N)=N)NC([C@@H](C)[C@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC1=O)=O)=O)=O)[C@H](C)C(N[C@@H](C(O)=O)CCC(N(C)C(C(N[C@@H]1C)=O)=C)=O)=O)=C\[C@@H]([C@H](CC2=CC=CC=C2)OC)C
InChi Code	InChI=1S/C49H75N13O12/c1-26(24-27(2)37(74-8)25-32-14-10-9-11-15-32)18-19-33-28(3)40(64)60-36(46(70)71)20-21-38(63)62(7)31(6)43(67)56-30(5)42(66)59-35(17-13-23-55-49(52)53)45(69)61-39(47(72)73)29(4)41(65)58-34(44(68)57-33)16-12-22-54-48(50)51/h9-11,14-15,18-19,24,27-30,33-37,39H,6,12-13,16-17,20-23,25H2,1-5,7-8H3,(H,56,67)(H,57,68)(H,58,65)(H,59,66)(H,60,64)(H,61,69)(H,70,71)(H,72,73)(H4,50,51,54)(H4,52,53,55)/b19-18+,26-24+/t27-,28-,29-,30+,33-,34-,35-,36+,37-,39+/m0/s1
InChi Key	JIGDOBKZMULDHS-UUHBQKJESA-N
Storage Temperature	-20 °C

Research Fields

Toxicology studies. Microcystin-RR can be used to investigate liver toxicity and elucidate the mechanisms underlying toxin-induced liver damage.
Environmental monitoring. In the realm of environmental science, microcystin-RR acts as a reliable indicator of cyanobacterial contamination in aquatic ecosystems. Its presence is instrumental in assessing water quality and aids in the formulation of effective remediation strategies to address and mitigate such contamination.
Biodegradation research. Researchers are also studying the biodegradation of microcystin-RR by bacteria, such as Sphingopyxis sp., which is critical for understanding how natural processes can remediate this harmful toxin.

Choose Alfa Chemistry

Alfa Chemistry is dedicated to delivering exceptional quality and driving continuous innovation. We are committed to harnessing the vast potential of marine resources to offer a diverse array of high-quality products. Currently, we can provide you with top-tier microcystin-RR at competitive pricing. If you have any specific requirements or inquiries, please do not hesitate to reach out to us. We are here to assist you!

For Research Use Only. Not for use in diagnostic or therapeutic procedures.