Mycalolide B

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Description

Mycalolide B is a naturally occurring macrolide compound known for its unique chemical structure and significant biological activities. It belongs to the family of secondary metabolites produced by marine sponges, specifically from the Mycale species. This compound has garnered attention in the scientific community due to its potent effects, particularly its ability to disrupt the actin cytoskeleton in eukaryotic cells. This property makes mycalolide B a valuable tool for studying cellular mechanisms related to cytoskeletal dynamics and has potential therapeutic applications in targeting diseases associated with actin dysregulation.

Specification

Item	Mycalolide B
Catalog	MC122752210
CAS	122752-21-0
Molecular Formula	C₅₂H₇₄N₄O₁₇
Molecular Weight	1027.16
Purity	>95%
Couple Target	ATPase
Couple Type	Inhibitor
Appearance	Clear to white solid
Solubility	Soluble in DMSO, methanol or isopropanol
Source	Isolated from the marine sponge Mycale sp.
MDL Number	MFCD00272618
SMILES	CC1C(CC=CC2=NC(=CO2)C3=NC(=CO3)C4=NC(=CO4)C(C(C(=O)C=CCC(CC(=O)OC1CC(C(C)CCC(C(C)C(C(C)C=CN(C)C=O)OC(=O)C)OC(=O)C(COC)OC)OC)O)C)OC)OC
InChi Code	InChI=1S/C52H74N4O17/c1-30(19-20-42(73-52(62)45(66-11)28-63-8)34(5)48(71-35(6)58)31(2)21-22-56(7)29-57)43(65-10)24-44-33(4)41(64-9)17-14-18-46-53-38(26-68-46)50-55-39(27-70-50)51-54-37(25-69-51)49(67-12)32(3)40(60)16-13-15-36(59)23-47(61)72-44/h13-14,16,18,21-22,25-27,29-34,36,41-45,48-49,59H,15,17,19-20,23-24,28H2,1-12H3/b16-13+,18-14-,22-21+/t30-,31+,32-,33+,34-,36-,41-,42+,43-,44-,45+,48+,49-/m0/s1
InChi Key	ZYDMLFOHENLMIN-RKRPCCGKSA-N
Stability	Store, as supplied, at -20 °C for up to 1 year. Store solutions at -20 °C for up to 3 months.
Storage Temperature	Store at -20 °C.

Research Applications

Mycalolide-B is a versatile compound extensively utilized in scientific research for various applications. It serves as a crucial tool in the study of actin polymerization and depolymerization mechanisms, enabling researchers to better understand these fundamental cellular processes. Additionally, mycalolide-B is employed in investigations of cell motility, cell division, and cytokinesis, owing to its ability to disrupt actin filaments effectively. Furthermore, it plays a significant role in the development of actin-targeting therapeutic agents and acts as a biological probe in the exploration of signal transduction pathways.

Choose Alfa Chemistry

At Alfa Chemistry, we are committed to upholding the highest quality standards while continuously seeking innovative solutions. Our mission is to unlock the vast potential of marine resources, providing a diverse range of premium products. We are pleased to offer mycalolide B at competitive prices and are committed to meeting your specific requirements. Should you have any inquiries or need further information, please feel free to reach out to us.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.