Okadaic Acid Ammonium

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Description

Okadaic acid ammonium is a toxin originally extracted from the marine sponge Halichondria okadai. This compound is known for its ability to inhibit protein phosphatases 1 (PP1) and 2A (PP2A), with a significantly higher affinity for PP2A. The inhibition of these enzymes can result in an increased phosphorylation state of various proteins, thereby influencing numerous biochemical reactions within cells. Furthermore, okadaic acid ammonium salt is recognized for its role as a tumor promoter. Notably, the ammonium salt form offers enhanced stability in solution compared to the free acid, making it more suitable for storage under prescribed conditions. This increased stability not only extends its shelf life but also ensures its efficacy in research and therapeutic applications.

Specification

Item	Okadaic Acid Ammonium
Catalog	MC155716066
CAS	155716-06-6
Molecular Formula	C₄₄H₆₇O₁₃·NH₄
Molecular Weight	822.04
Purity	>98%
Solubility	Soluble in ethanol, DMSO, water.
Appearance	White to off white solid
Melting Point	50-70 °C
MDL Number	MFCD00153856
SMILES	C[C@@H]1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)[O-])O)O)C)O)O.[NH4+]
InChi Code	InChI=1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33-,34-,35-,36-,37+,38+,39-,41-,42+,43+,44-;/m1./s1
InChi Key	ZBOMSHVRJSJGNR-BNESWMAXSA-N
Storage Temperature	-20 °C

Research Fields

In the field of chemistry, okadaic acid ammonium serves as a fundamental building block for the synthesis of more intricate molecules. Its distinctive structure enables it to interact with specific biological targets, positioning it as a promising candidate for drug development in the realms of biology and medicine. Additionally, okadaic acid ammonium offers valuable insights into various cellular processes, including the cell cycle, apoptosis, nitric oxide metabolism, and calcium signaling. This multifaceted role not only underscores its significance in research and therapeutic applications but also highlights its potential to advance our understanding of cellular mechanisms.

Choose Alfa Chemistry

Alfa Chemistry is dedicated to delivering exceptional quality and continuously pushing the boundaries of innovation. Our mission is to harness the vast potential of marine resources, offering a diverse array of premium products. We take pride in our ability to supply high-quality okadaic acid ammonium at competitive prices. Should you have any specific needs or inquiries, please do not hesitate to reach out to us.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.