Description

ω-Conotoxin CVIA is a 27-amino acid neuropeptide derived from the venom of Conus catus. The toxin acts as a blocker of voltage-sensitive calcium channels (VSCCs). The selective blocking of these calcium channels by ω-conotoxin CVIA has significant implications for neuroscience research and potential therapeutic applications, particularly in the management of chronic pain. By preventing calcium influx into neurons, ω-conotoxin CVIA can effectively disrupt synaptic transmission and modulate pain signals, showcasing its potential as a valuable tool in pain management strategies and in the study of calcium channel physiology.
Specification
Item | ω-Conotoxin CVIA |
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Catalog | MC325164065 |
CAS | 325164-06-5 |
Molecular Formula | C97H161N39O36S6 |
Molecular Weight | 2641.95 |
Purity | >99% |
Sequence | Cys-Lys-Ser-Thr-Gly-Ala-Ser-Cys-Arg-Arg-Thr-Ser-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Arg-Cys-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
Sequence Shortening | CKSTGASCRRTSYDCCTGSCRSGRC-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
Length (AA) | 25 |
Peptide Content | 100% |
Form | Lyophilized powder |
Source | Synthetic peptide |
Storage | Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20 °C. Protect from moisture. |
Solubility | Any aqueous buffer |
Storage of Solutions | Store up to two weeks at 4 °C or up to three months at -20 °C. |
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.