Description

ω-Conotoxin SO3, a conopeptide containing 25 amino acids, can be isolated from the venom of Conus striatus. It specifically targets voltage-gated calcium channels, inhibiting neurotransmitter release and thus playing a crucial role in modulating pain pathways. Notably, ω-conotoxin SO3 is more selective for N-type voltage-sensitive calcium channels than ω-conotoxin MVIIA, a selective N-type voltage-sensitive calcium channel blocker. The mechanism of action of ω-conotoxin SO3 has garnered significant interest in pain management and as a potential therapeutic agent in treating various neurological disorders.
Specification
Item | ω-Conotoxin SO3 |
---|
Catalog | MC441284328 |
CAS | 441284-32-8 |
Molecular Formula | C100H166N36O31S6 |
Molecular Weight | 2561.00 |
Purity | >95% |
Sequence | Cys-Lys-Ala-Ala-Gly-Lys-Pro-Cys-Ser-Arg-Ile-Ala-Tyr-Asn-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
Sequence Shortening | CKAAGKPCSRIAYNCCTGSCRSGKC-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
Length (AA) | 25 |
Peptide Content | 100% |
Form | White lyophilized solid |
Source | Synthetic peptide |
Storage | Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20 °C. Protect from light and moisture. |
Solubility | Water and saline buffer |
Storage of Solutions | Store up to two weeks at 4 °C or up to three months at -20 °C. |
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.