Description
Saxitoxin dihydrochloride is a potent neurotoxin that is primarily produced by certain species of marine dinoflagellates, as well as some freshwater cyanobacteria. Saxitoxin dihydrochloride is known to cause paralytic shellfish poisoning (PSP). It works primarily at the molecular level by targeting voltage-gated sodium channels. Upon binding to these channels, it effectively blocks the entry of sodium ions into the cell. This blockage suppresses the generation and propagation of action potentials, ultimately leading to muscle paralysis. Uniquely, saxitoxin dihydrochloride has potent neurotoxic effects even at very low concentrations. This makes it a valuable tool for neurophysiological studies and of great public health concern for its role in paralytic shellfish poisoning.
Specification
| Item | Saxitoxin Dihydrochloride |
|---|
| Catalog | MC35554086 |
| CAS | 35554-08-6 |
| Molecular Formula | C10H17N7O4·2HCl |
| Molecular Weight | 372.21 |
| Purity | >99% |
| Concentration | 20.9±1.6 µg/g |
| Solubility | Very soluble in water and methanol. Slightly soluble in ethanol and glacial acetic acid. |
| Appearance | White hygroscopic solid |
| Canonical SMILES | C1CN2C(=NC(C3C2(C1(O)O)NC(=N3)N)COC(=O)N)N.Cl.Cl |
| Isomeric SMILES | C1CN2C(=N[C@H]([C@H]3[C@]2(C1(O)O)NC(=N3)N)COC(=O)N)N.Cl.Cl |
| MDL Number | MFCD05662361 |
| InChi Key | YHAHUGQQOBPXOZ-UIPPETONSA-N |
| Storage Temperature | Store at -20 °C |
Applications
- In the field of chemistry, saxitoxin dihydrochloride serves as a critical standard in analytical methods to detect and quantify paralytic shellfish toxins.
- In medicine, saxitoxin dihydrochloride is employed in neurophysiological research to investigate the functionality of sodium channels. These studies are vital for elucidating the mechanisms of nerve signal transmission, potentially paving the way for advancements in neurology.
- From an Industrial perspective, Saxitoxin dihydrochloride contributes to the development of diagnostic kits designed for detecting paralytic shellfish poisoning in seafood.
Choose Alfa Chemistry
At Alfa Chemistry, we are committed to upholding the highest standards of quality while constantly innovating to provide cutting-edge solutions. Our mission is to tap into the vast potential of marine resources, offering a diverse range of premium products. We are proud of our ability to supply high-quality saxitoxin dihydrochloride at competitive prices. If you have any questions or specific requirements, please feel free to contact us. We are eager to assist you!
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
