Description

μ-Conotoxin BuIIIA is a marine toxin isolated from the venom of the cone snail Conus bullatus. This natural peptide has been recognized for its potent ability to block voltage-gated sodium channels (VGSCs) in nerve cells, which are crucial for nerve impulse transmission. The specificity and high affinity of μ-conotoxin BuIIIA for particular sodium channel subtypes make it a valuable tool in neurophysiological research. It is often used in the study of neurological diseases.
Specification
Item | µ-Conotoxin BuIIIA |
---|
Catalog | MC046 |
Molecular Formula | C106H172N44O31S6 |
Molecular Weight | 2751.17 |
Purity | >98% |
Sequence | Val-Thr-Asp-Arg-Cys-Cys-Lys-Gly-Lys-Arg-Glu-Cys-Gly-Arg-Trp-Cys-Arg-Asp-His-Ser-Arg-Cys-Cys-NH2 (Disulfide bridge: Cys5-Cys16, Cys6-Cys22, Cys12-Cys23) |
Sequence Shortening | VTDRCCKGKRECGRWCRDHSRCC-NH2 (Disulfide bridge: Cys5-Cys16, Cys6-Cys22, Cys12-Cys23) |
Length (AA) | 23 |
Peptide Content | 100% |
Form | Lyophilized powder |
Source | Synthetic peptide |
Storage | Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20 °C. Protect from moisture. |
Solubility | Any aqueous buffer |
Storage of Solutions | Store up to two weeks at 4 °C or up to three months at -20 °C. |
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.